Home > News > CCG News > ‘Don’t delay’, invitees in Leicester are told, as mobile clinic for ground-breaking NHS-Galleri cancer study arrives in town

‘Don’t delay’, invitees in Leicester are told, as mobile clinic for ground-breaking NHS-Galleri cancer study arrives in town

11th May 2022 | By Liz Mattock | Posted in

Participants in the world’s largest trial of a revolutionary new blood test, GalleriTM, which can detect more than 50 types of cancer often before symptoms appear, will be starting to arrive for their appointments outside Tesco’s in Hamilton, Leicester, from Monday 16th May.

Selected residents aged 50-77 registered at GP practices in Leicester, who have received a letter from the NHS inviting them to participate in the NHS-Galleri trial, are urged to book their appointment and take part before the mobile clinic moves on to its next destination on 16th June.

Dr Paul Danaher, GP and Clinical Lead for Cancer for Leicester City Clinical Commissioning Group, said: “By taking part in this trial, the people of Leicester will be at the forefront of developing a test that has the potential to save lives from cancer in the UK and around the world. So, if you are invited, please take part – you could be helping us to revolutionise cancer care.”

As well as the clinic at Tesco’s in Hamilton, there will also be a clinic at Leicester Central Mosque, and at East Leicester Medical Practice in Highfields.

Participants, who must not have had a cancer diagnosis or treatment in the last three years, will be able to watch an animation about the trial, ask questions and, if happy to consent, give a blood sample at their first appointment. They will be invited back after 12 months, and again at two years, to give two further blood samples.

Kelly Lambert, Associate Medical Director for Cancer, University Hospitals of Leicester NHS Trust, said: “The NHS-Galleri trial is a great opportunity for people in Leicester to help us in our aim to diagnose more cancers at an earlier, treatable stage. Please get involved if you are invited – as well as helping us to better understand how tests like this can be part of cancer diagnosis, for some people in the trial it could potentially be lifesaving.’

The Galleri™ test checks for the earliest signs of cancer in the blood. The NHS-Galleri trial, the first of its kind, will assess how well the test works in the NHS and whether the technology can be used as a tool to screen people with no cancer symptoms. The trial aims to recruit 140,000 participants nationally, including those who have now signed up in Leicester. The trial team is keen to attract participants from different background and ethnicities to ensure results are relevant for as many different people as possible.

The NHS-Galleri trial is a Randomised Control Trial (RCT) – meaning that half the participants will have their blood sample screened with the Galleri test right away and the other half will have their sample stored and may be tested in the future. This will allow scientists to compare the stage at which cancer is detected between the two groups. All participants will be advised to continue with their standard NHS screening appointments and to still contact their GP if they notice any new or unusual symptoms.

Michael Ryan, Head of East Midlands Cancer Alliance, said: “We know from other trial locations that slots at the mobile clinics book up rapidly so, if you have been invited, please do register for the trial as soon as you can. It is easy to book online or by phone by following details in your invitation letter or checking out nhs-galleri.org. You could be part of a study that has the potential to transform early cancer diagnosis.”

The test is a simple blood test that research has shown is particularly effective at finding cancers that are difficult to identify early – such as head and neck, bowel, lung, pancreatic, and throat cancers.

It works by finding chemical changes in fragments of genetic code – cell-free DNA (cfDNA) – that leak from tumours into the bloodstream.

The NHS-Galleri trial is being run by The Cancer Research UK and King’s College London Cancer Prevention Trials Unit in partnership with the NHS and healthcare company, GRAIL, which has developed the Galleri test. Anyone whose results indicate a possible cancer will be followed up urgently in the NHS.

Sir Harpal Kumar is President of GRAIL Europe, the company that has developed the Galleri™ test. He said: “We are eager to bring our technology to people in the UK as quickly as we can. We’re delighted to partner with the NHS to support the NHS Long Term Plan for earlier cancer diagnosis and grateful to thousands of members of the public coming forward to participate in the trial.”

Initial results of the study are expected by 2023 and, if successful, NHS England plans to extend the rollout to a further one million people in 2024 and 2025.

The trial is the latest initiative launched by the NHS to meet its Long Term Plan commitment of finding three-quarters of cancers at an early stage by 2028.

Patients whose condition is diagnosed at ‘stage one’ typically have between five and 10 times the chance of surviving at least five years compared with those found at ‘stage four’.

How to take part

Appointments at Tesco’s in Hamilton are by invitation letter only, until June 16.

Appointments at other Leicester clinics are open access – an invitation letter is not required.

The clinic will be at:

  • East Leicester Medical Practice: Friday June 10 and Friday June 17
  • Leicester Central Mosque: Monday June 13  to Thursday June 16

Further information is available in English, Punjabi, Gujarati, Bengali and Urdu https://www.nhs-galleri.org/downloads/participant-information-sheet.

Booking is via the website https://www.nhs-galleri.org/ using a unique code on the invitation letter, or by telephone without a code (open registration particularly for the East Leicester Medical Practice or Mosque sites) – 0800 030 9245

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